Computational investigations of polymerase enzymes: Structure, function, inhibition, and biotechnology
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Function and biotechnology of extremophilic enzymes in low water activity
Enzymes from extremophilic microorganisms usually catalyze chemical reactions in non-standard conditions. Such conditions promote aggregation, precipitation, and denaturation, reducing the activity of most non-extremophilic enzymes, frequently due to the absence of sufficient hydration. Some extremophilic enzymes maintain a tight hydration shell and remain active in solution even when liquid wa...
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ژورنال
عنوان ژورنال: WIREs Computational Molecular Science
سال: 2021
ISSN: 1759-0876,1759-0884
DOI: 10.1002/wcms.1534